Toronto Maple Leafs forward Ilya Mikheyev left Saturday's pre-season game against the Ottawa Senators with a hand injury and did not return.

TSN's Kristen Shilton tweets Mikheyev got crunched into the boards towards the end of the first period.

After the game, Maple Leafs head coach Sheldon Keefe told reporters that Mikheyev's injury is expected to keep him out long-term.

"We'll know more on Monday, but it's not looking like it will be short term at this point ... It's a big loss. He's had a great camp. He's a good player for us, does a lot of things for us, but we have a lot of depth. We've had a lot of guys with good camps. We have a lot guys already down with the Marlies that had good camps. We have guys that are still with us here that didn't play tonight, who have had good camps so it's going to create opportunities for others to step up," Keefe said.

The 26-year-old winger had one assist in 5:04 of ice time prior to his departure. Mikheyev started the last two pre-season games on the second line with John Tavares and William Nylander. 

A native of Omsk, Russia, Mikheyev had seven goals and 10 assists in 54 games with the Maple Leafs last season.

After defeating Ottawa 4-1 Saturday night, Toronto will open the regular season against the Montreal Canadiens on Wednesday.